Data Management and Analysis Core

The Data Management and Analysis Core (DMAC) facility, is funded through the Nebraska Center for Integrated Biomolecular Communication (CIBC) and will develop and support the data management and analysis needs of faculty and students involved in biomolecular communication research. Researchers in the CIBC are embracing the challenges and promise of large-scale, high-throughput data, and the DMAC facility has been designed to serve as an integral partner in such research. These partnerships will require that the DMAC facility 1) provide expertise in data management, statistical analyses, data mining and machine learning, functional and predictive analyses, querying of existing databases, and computational modeling and 2) educate CIBC members about the role of omics data in research and successful approaches to collaboration with faculty and staff in bioinformatics.

DMAC Services

The Nebraska Center for Integrated Biomolecular Communication (NCIBC, ), an NIH Center of Biomedical Research Excellence (CoBRE), is considering adding new services to its Data Management and Analysis Core (DMAC) facility. We are asking for guidance from NCIBC members and other potential users of the DMAC. Please respond via the link below to a brief (3 minute) survey related to the methodologies and services of interest/potential interest to you in your research. Feel free to forward this request to other potentially interested faculty.

 This survey will help us understand how NCIBC can best support research programs across campus. If you have questions, please do not hesitate to contact us. Thank-you in advance for your time and participation.

Design and Implement a Computational Platform for Data Management

The DMAC facility’s computational platform will consist of a web portal that enables data access, processing, and interpretation within the Center and also facilitates the sharing of research data with stakeholders and the general public. Significantly, the web portal will facilitate interactions with the SBC facility by permitting CIBC members to upload data from microscopy, MS, and nuclear magnetic resonance (NMR) experiments for investigator access.

Establish a Process for Initiating Collaborations with DMAC Personnel

This process will include a web request form for DMAC services; personal contact (in person and/or by email) between the DMAC and the requester to establish a common understanding of the needs, goal, and cost of the request; request prioritization; and expected timeline for completion.

Serve a Critical, Sustainable Role in CIBC Research by Contributing as Research Collaborators on Proposed CIBC Projects

The members of the DMAC will contribute to CIBC projects as collaborators, enabling both basic and complex data analyses. We expect that DMAC efforts will constitute intellectual contributions worthy of both authorship and inclusion on proposals for additional research funding.

Education CIBC Members About the Role of Large-scale Omics Data in Chemical and Biochemical Research

A key function of the DMAC facility is to provide the research community with educational opportunities about statistics, informatics, and the role of a core such as this in chemical and biochemical research. The education proposed will enable researchers to use existing tools for basic analyses and optimize the quality of their interactions with DMAC personnel.

Expected Impact

The DMAC facility will have a high, positive impact on Center development by enabling affiliated researchers to address critical problems in biomolecular communication relevant to our basic understanding of human disease processes. The DMAC facility will also emphasize the multi- and interdisciplinary nature of the research necessary to address such problems and commit resources to establishing and supporting teams of researchers within the CIBC.

The expected outcomes of the CIBC’s DMAC facility include 1) the creation of a computational pipeline for data storage and management that serves all CIBC investigators; 2) a rational, sustainable process for collaboration with DMAC personnel, which will lead to interdisciplinary publications and proposals for external funding; and 3) educational opportunities for CIBC faculty and staff in omics data research, management, and analysis. In the long-term, the DMAC facility is expected to recover half of its operating expenses through web portal access fees, data storage fees, and analytical service fees, which will contribute greatly to its sustainability.

Data Management and Analysis Core